SCIENTIFIC POSTER
T cell-induced morphological change analysis of colorectal cancer organoids using AI
Successfully classify various CRC organoid morphologies using AI-enabled analysis in live T-cell screening workflows
In this poster, we address the challenges associated with the use of PDOs in large-scale applications and share a novel live T-cell screening workflow using bioreactor-expanded patient-derived colorectal cancer organoids (CRCs). These organoids were successfully classified according to various morphological characteristics and segmented to quantify the efficacy of T-cells in solid tumors. The whole system—along with the percentage analysis of morphologically modified organoids across time—can be used as a successful live T-cell screening approach.
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Product family
Imaging
Product primary application
ImageXpress Micro Confocal High-Content Imaging System; IN Carta Image Analysis Software
CMP
701Rn00000Pi5lbIAB
Title
T cell-induced morphological change analysis of colorectal cancer organoids using AI
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