High-content Imaging
High-content imaging systems ranging from automated digital microscopy to high-throughput confocal imaging systems
High-content imaging (HCI) systems
High-content imaging is an advanced technique used in cellular imaging systems to capture and analyze extensive visual data from biological samples. It combines cutting-edge microscopy technology, sophisticated image analysis algorithms, and powerful data processing capabilities to rapidly quantify multiple parameters relating to cellular structures, functions, and responses.
Our ImageXpress® high-content imaging systems range from automated digital microscopy to high-throughput confocal imaging systems. Our state-of-the-art AgileOptix™ technology combines an advanced solid-state light engine, water immersion objectives, a scientific CMOS sensor, and proprietary, dual-spinning disk technology. These systems allow researchers to explore the complex world of cellular biology, capturing high-resolution images of cells and subcellular components with a high level of accuracy and detail.
The acquired images are then subjected to in-depth analysis using high-content analysis (HCA) software. This software encompasses powerful algorithms that can extract a wide range of quantitative measurements. With our AI-enabled solutions, researchers can obtain valuable insights into various cellular features, including cell morphology, protein expression levels, subcellular localization, and cellular responses to different treatments or stimuli with increased efficiency.
One key advantage of high-content imaging is its high-throughput capabilities. Researchers can analyze large numbers of cells and images in a relatively short period, enabling them to study complex cellular processes at an unprecedented scale. This feature is particularly useful in drug discovery, toxicology studies, and basic research, as it allows for efficient screening of compounds or investigation of cellular mechanisms.
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