Desktop
ImageXpress HCS.ai High-Content Screening System
Mobile

ImageXpress HCS.ai High-Content Screening System

A fast, intuitive and versatile system delivering deeper insights for every lab

Speak to an expert

Download the brochure

https://vids.moleculardevices.com/watch/hydcpAEGH8Kjvp7sPhN5zH

Deeper insights for every lab

The ImageXpress® HCS.ai High-Content Screening System captures your imagination with high-quality imaging and analysis, enabling you to acquire the crystal-clear images and robust data you need with ease.

Powered by intuitive MetaXpress® Acquire software, the ImageXpress HCS.ai system integrates seamlessly with AI-driven IN Carta® Image Analysis Software for deep insights. An advanced, modular design offers the flexibility to perform a vast range of 2D and 3D assays in a single solution, while allowing for easy upgrades to meet evolving laboratory needs.

Modular Icon

Modular and intuitive for optimal versatility

The ImageXpress HCS.ai system features a modular design and a wide array of customizable configuration options to meet your current needs and on-site upgrades to match your future requirements. The newly upgraded MetaXpress® Acquire software is an intuitive solution for users of all experience levels, providing direct access to reliable and insightful data.

Cell organoids icon

Higher quality images and superior data analysis for deeper insights

Acquire high-quality images across a vast range of assay types, obtain exceptional image quality from your 3D samples, and unlock new discoveries with AI-powered IN Carta® Image Analysis Software.

Increase throughput Icon

Faster acquisition for accelerated high-throughput workflows

Boost lab productivity by imaging more plates in less time and simplifying the learning curve for new users. A new, automation friendly design enables you to integrate easily into automated workflows for faster, more reliable results.

Discover the new ImageXpress HCS.ai High-Content Screening System

Features

Enable Greater Icon

Multiple imaging modes

The system offers brightfield label-free imaging, widefield and confocal fluorescent imaging.

Automated Water Immersion Objective Icon

Automated water immersion objective technology option

Offers greater image resolution and sensitivity with up to 4x increase in signal, which leads to lower exposure times.

Modular Icon

Streamlined upgrade pathway

The modular design enables additional capabilities to be easily added to your system, allowing easy upgrades as your needs evolve.

Optics Icon

Exclusive AgileOptix™ spinning disk technology

Provides increased sensitivity with specially designed optics, high-powered laser illumination, and sCMOS sensor. Swappable disk geometries provide flexibility between speed and resolution.

High-intensity Laser Light Icon

High-intensity laser light source option

The option of laser illumination enables you to capture images faster with shorter exposure times and multiplex your experiments with 7 lasers and 8 imaging channels.

option icon

Magnification changer option

Get access to 12 magnifications within a single configuration, including high NA (Numerical Aperture) and ELWD (Extra-Long Working Distance) options.

Analysis icon

MetaXpress® Acquire Acquisition and Analysis Software

The MetaXpress® Acquire acquisition package streamlines complex workflows—new users can get started quickly, whereas advanced users can leverage its flexibility to create optimized protocols.

AI-powered Icon

AI-powered IN Carta® image analysis software

Leverages machine-learning to improve the accuracy and robustness of high-content image analysis, delivering data insights that other technologies miss. Reduces the complexity of image analysis with intuitive guided workflows in a modern user interface.

MetaXpress Acquire High-Content Image Acquisition Software

MetaXpress® Acquire High-Content Image Acquisition Software is a comprehensive solution for high-content imaging, designed for use with our ImageXpress HCS.ai High-Content Screening System. An intuitive interface and guided workflows streamline even complex imaging assays, enabling you to start generating data in minutes.

Learn more about MetaXpress Acquire

MetaXpress Acquire High-Content Image Acquisition Software

IN Carta image analysis software

Powerful analytics combined with an intuitive user interface simplify workflows for image analysis and phenotypic profiling. Advanced features provide the functionality you need to analyze data in 2D, 3D, and 4D - at scale - and deliver real-time insights without the need for complex pre- or post- processing operations. Improve specificity of your image analysis workflows by utilizing the SINAP deep-learning module and see for yourself that Segmentation Is Not A Problem. Put machine learning to work for you and perform complex phenotypic analysis within a user-friendly Phenoglyphs module.

Learn more about IN Carta

IN Carta image analysis software

Latest Resources

Applications of ImageXpress HCS.ai High-Content Screening System

Specifications & Options of ImageXpress HCS.ai High-Content Screening System

Model
ImageXpress.HCS.ai Widefield
ImageXpress.HCS.ai Confocal
ImageXpress.HCS.ai Advanced
Widefield capability
Yes
Yes
Yes
Water immersion option (20X-60X)
Yes
Yes
Yes
Magnification changer option (1X and 1.5X)
Yes
Yes
Yes
Environmental control option
Yes
Yes
Yes
LED illumination
Yes
Yes
Standard spinning disk confocal (60μm pinhole (single), 60μm pinhole + 50μm slit (dual)
Yes
Yes
Deep tissue spinning disk 50μm pinhole Deep Tissue disk (dual)
Yes
Laser illumination
Yes

Resources of ImageXpress HCS.ai High-Content Screening System