Comparison of reference compounds on cardiomyocyte beat rate

(A) Calcium signal change in untreated iPSC cardiomyocytes incubated for two hours with EarlyTox Cardiotoxicity Dye indicated by calcium peaks. (B) Propranolol slows peak frequency of calcium in iPSC cells. (C) Isoproterenol increases calcium peak frequency in iPSC cardiomyocytes. (D) Sotalol slows peak frequency of calcium in iPSC cardiomyocytes and alters the normal pattern.