Viral pathogenesis (Viral pathways)

Understanding the basic mechanisms of viral entry, replication, shedding, etc. is critical for the development of effective treatments towards infectious diseases. Fluorescence microscopy is a fundamental tool in any virology laboratory because it allows for visualization of viral pathways at high resolution and over time. Cell signaling and reporter gene assays can be used to explore cellular pathways affected by viruses and are run using microplate readers.

Here’s a few application notes on viral pathogenesis (Viral pathways) to aid in your COVID-19 vaccine research:

• Internalization - Visualize subcellular vesicles to quantitate autophagy in neuronal cells
• Reporter gene assays - Measuring luciferase expression using the SpectraMax Glo Steady-Luc Reporter Assay Kit
• Cell signaling (GPCR) - Complete cAMP workflow solution using the CatchPoint cAMP Fluorescent Assay Kit