Patient-derived organoids (Tumoroids)

Patient-derived tumor organoids or tumoroids are cultures of tumor cells derived from individual patients. Patient-derived organoids (PDOs) are generated from tumor biopsies or surgical procedures and can serve as models to understand patient-specific drug responses and investigate cancer cell growth. Digested tumor pieces and cells harvested from patient-derived tumors exhibit cancer stem cell (CSC)-like qualities and can be expanded over multiple passages to produce large numbers of organoids that maintain molecular characteristics of the original tumor.

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