Neurotoxicity, neuronal toxicity

High-content imaging using iPSCs of human origin can be applied to examine neurotrophic, neuroprotective, or neurotoxic effects of pharmaceutical drug candidates or environmental contaminants. This note demonstrates neuronal toxicity screening via automated endpoint and live-cell assays using iPSCs and Molecular Devices instruments and software.

• High-content screening of neuronal toxicity using iPSC-derived human neurons
• Poster – Multiplexed automated assays for neurotoxicity evaluation using induced pluripotent stem cell-derived neural 3D cell models
• Webinar: Human iPS cell-derived neurons: a new physiologically relevant model for drug discovery applications for high-content screening of neurotoxicity
• Webinar: An AI-based approach to high-content phenotypic characterization of human iPSC-derived neuronal cells