EarlyTox™ Cardiotoxicity Kits provide a homogeneous solution to predict compound toxicity and efficacy

EarlyTox Cardiotoxicity Kits utilize a calcium sensitive dye that is absorbed into the cell's cytoplasm during incubation. When dye binds with calcium ions in the cell cytoplasm, fluorescent intensity increases, enabling measurement of any changes in calcium concentration. The masking technology does not enter the cell, but reduces extracellular background fluorescence. This helps improve the assay signal window, providing more detail to the beat patterns.