3D Live Cell Assays

3D Live Cell Assays

The integration of three-dimensional (3D) assay models is becoming more widespread to drive translational biology. This has led to significant progress in the development of higher complexity and biologically relevant 3D cell models to better mimic in vivo environments and responses to drug treatments. Recently, simple, automated workflows, suitable for high-content imaging have become popular. Acquiring measurements from these 3D structures involve acquiring images from different depths (z-planes) and analyzing them in 3D or collapsing the images into a single 2D stack before analysis.