Electrophysiology Studies

ON-DEMAND WEBINAR

Empower your electrophysiology studies using new Axon pCLAMP 11 software

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Empower your electrophysiology studies using new Axon pCLAMP 11 software

The focus of the Axon pCLAMP™ software suite is to provide users with greater capability in electrophysiology data acquisition and analysis. The new features in Clampex 11 software enhances functionality in Protocol Editor, increasing the user's ability to create complex experimental protocols involving many command stimulations. With these new features, researchers are able to perform more experiments, discover more findings, and get more data through their electrophysiology studies.

In this webinar, Dr. Jeffrey Tang demonstrates how to use these new features.

Key highlights:

https://share.vidyard.com/watch/TVRg4mbWNhJfqah6YHdmCr

Q&A

Q. I have pCLAMP 9 and 10 versions in my lab. Could I upgrade them to pCLAMP 11 version?

A. If you already have the pCLAMP 9 or using pCLAMP 10, you don’t need to buy a new license. You can upgrade it from pCLAMP 9 or from pCLAMP 10 to pCLAMP 11. Unless you are building a new rig that you need a new license. Otherwise you can contact our sales and ask for the upgrade cost. The upgrade cost will be much cheaper than a new license cost.

Q. Can you provide some details about HumSilencer™?

A. HumSilencer is our newly developed technology to eliminate the 50/60 Hz cycle noise. You can email me or Technical Support at support@moldev.com. I can send you a couple of applications notes about the superior performance of HumSilencer in real experiments for example in single channel recording and field potential recording. These two application notes will show you how great the HumSilencer is in eliminating the line-frequency noise.

Q. Are you planning on adding a peak scaled NSFA to pCLAMP 11?

A. Please send an email to the Support team.

Q. Does Clampex 11 compatible to Digidata 1440?

A. Clampex 11 is compatible to Digidata 1440 and 1550 series, not to DD1322 series. So, if you already have 1440 you can use the pCLAMP 11.

Q. How do we use HumSilencer? How do you minimize noise as much as possible?

A. The HumSilencer basically will only eliminate the line frequency noise. This technology is integrated in the Digidata, so when you turn on the Digidata, the Digidata or the HumSilencer will start to learn the line frequency noise from the power line. If HumSilencer detects the 50/60 Hz cycle noise, it will automatically learn and subtract the noise from the recording trace.

Q. Could the command waveform in the gap-free mode be saved?

A. Unfortunately in the gap-free mode that I showed you in the presentation, the waveform cannot be saved. However, I can give you the workaround. You can connect the secondary output to a unused analog input channel. The command voltage or current waveform can be recorded.

Q. It’s great that Clampfit 11 can be installed & used in multiple computers. The white dongle is required to use new features in Clampfit. Could I get an extra white dongle for Clampfit 11 if I want to use those extra features in other computers?

A. In the Clampfit 11, without the dongle, it behaves just like the Clampfit 10. If you want to use the new features like the Batch Analysis, Action Potential Search, or the Population Spike Search, the white dongle has to be used. Now if I want to have two dongles, one in the lab, and one at home, to analyze the data. You can buy an extra white dongle, which can be ordered separately. It’s not expensive at all. I would rather pay a little bit more for an extra dongle.

Q. Are there any new spectral analysis features?

A. Yes, there is spectral analysis in Clampfit. Please submit an email to Support for further information.

Q. I am conducting a pharmacological experiment with perfusion of many drugs in one cell. Can I pre-program more digital outputs for drug perfusion using the gap-free mode?

A. If you remember when I did the demo in the presentation, I only used the digital output channel zero. There are total 8 digital output channels from 0 to 7 enabled in gap-free mode. Now you can pre-program digital outputs from channel 0 to 7. You can use maximal 8 digital output to trigger 8 drug perfusion on one cell. Again, if you have any questions about this, please email support@moldev.com.