ON-DEMAND WEBINAR
Mastering Monoclonality: The Next Generation of Single-Cell Dispensing and Imaging with the DispenCell and CloneSelect Imager
Single-cell isolation and imaging are revolutionizing our understanding and manipulation of cellular processes. Technologies like the DispenCell Single-Cell Dispenser and CloneSelect Imager are pivotal in offering unparalleled precision and efficiency in cell line development and monoclonality verification. These innovative tools are critical for anyone aiming to delve deeper into cellular behaviors and interactions, especially in fields like drug discovery and personalized medicine. However, the challenge of ensuring precise, gentle, and efficient single-cell isolation and imaging has been a significant barrier. This is where DispenCell and CloneSelect stand out, providing solutions that overcome these obstacles.
Key Takeaways Include:
- Innovative Single-Cell Dispensing: DispenCell is a game-changer in single-cell isolation, offering the gentleness of manual pipetting with automated precision. It efficiently handles mammalian cells ranging from 8 to 25 um in diameter, ensuring broad applicability in various research contexts.
- Enhanced Sample Preparation: Learn how to prepare your cell samples with ease, using tools like a 20 um mesh size cell strainer and specific buffers to maintain cell viability. The step-by-step guide in our demo walks you through the process, highlighting the importance of cell concentration and viability for optimal results.
- User-Friendly Interface: The software accompanying DispenCell is designed for ease of use, guiding you through each protocol step. This includes installing the DispenTip, setting up the multiwell plate, and adjusting detection parameters for precise cell dispensing.
- Advanced Cell Analysis and Dispensing: DispenCell's technology ensures accurate cell dispensing with real-time monitoring, allowing for the dispensing of a 96-well plate in just 5 to 10 minutes. The software's sophisticated analysis tools enable you to refine detection thresholds and identify single cells with precision.
- Rapid Monoclonality Verification with CloneSelect Imager: Post-dispensing, the CloneSelect Imager steps in to provide fast, image-based proof of monoclonality, scanning a 96-well plate in under 90 seconds. This capability is crucial for regulatory compliance and efficient workflow in biologic product development.
- Comprehensive Software Integration: The CloneSelect Imager software offers a seamless experience with step-by-step guidance for microplate imaging. Its compatibility with standard SBS plates and integrated barcode reader makes data tracking and analysis straightforward and efficient.