![3D neurospheres](./media_1a90d833e15dbe096fe5b8ccf66f3e4f12251e20c.jpeg?width=750&format=jpeg&optimize=medium)
SCIENTIFIC POSTER
Functional characterization of healthy and disease-related 3D neurospheres assembled using human iPSC-derived neurons and astrocytes
![Functional characterization of healthy and disease-related 3D neurospheres](./media_1b954ccc2cbcc21545ee026b4b6ce3fac7d8c65ea.png?width=750&format=png&optimize=medium)
Neural 3D spheroids are a rapidly developing technology with great potential for understanding brain development and neuronal diseases.
https://vids.moleculardevices.com/watch/h69HhcjkQz3J7ceBTdQMcw
They provide a more advanced and biologically relevant system for basic research and high-throughput drug discovery, including compound profiling and toxicity testing.
In this poster, we explore how this biological system of 3D neurospheres paired with a detailed analysis of calcium oscillations demonstrates a promising and informative tool for disease modeling and phenotypic functional evaluation that could be used for compound testing.