SCIENTIFIC POSTER
Rapid Assessment of viability in patient-derived colorectal cancer organoids
Cancer cell lines grown in 2D have long served as experimental surrogates for cancers. In recent years, the 3D culture of cancer cells is enabling new models for cancer research that are considered more biologically relevant.
In this scientific poster, we use patient-derived colorectal cancer organoids to assess differential effects of known anti-cancer compounds on organoid size and morphology using both imaging and a microplate reader-based viability readout. This streamlined readout may be used to guide identification of potential therapeutics early in the screening process, which could then be followed up with more intensive high content imaging or other analyses.
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Product family
Microplate Reader
Product primary application
ImageXpress Micro Confocal High-Content Imaging System; MetaXpress High-Content Image Acquisition and Analysis Software; SpectraMax i3x Multi-Mode Microplate Reader
CMP
7014u000001JybiAAC
Title
Rapid Assessment of viability in patient-derived colorectal cancer organoids
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