University of Copenhagen uses the SpectraMax Paradigm reader to investigate cancer metastasis

The Challenge

The University of Copenhagen’s Biotech Research & Innovation Centre (BRIC) was established in 2003 by the Danish Ministry of Science, Technology and Innovation to form an elite center in biomedical research. Working within BRIC is the research group of Dr. Janine Erler, a cancer biology group who are interested in elucidating the underlying processes contributing to tumor progression and patient treatment failure. Speaking about the group’s research, Anette Høye, a Postdoctoral Researcher in the Erler lab, explains “We are interested in understanding how cancer spreads through the body (a process called metastasis) as this is responsible for over 90% of cancer patient deaths. We are particularly interested in dissecting how the microenvironment surrounding tumor and normal cells affect metastatic behavior. Through integration of multiple types of data we hope to identify biomarkers and effective therapeutic strategies targeting metastasis”.

The Solution

Scientists in the Erler group use the SpectraMax® Paradigm Multi-Mode Microplate Reader with ScanLater™ Western Blot Detection Cartridge as a tool to investigate protein expression levels and signaling pathways related to their research. Understanding how tumors acquire the ability to invade and metastasize is critical for the identification of new targets and development of therapies against metastatic disease.

SpectraMax Paradigm Multi-Mode Microplate Reader

Details

Products Used

Future-proof your lab with the SpectraMax® Paradigm® Multi-Mode Microplate Reader. Get the system that delivers the data you need today, and when you need more, transform your reader with a detection-mode addition upgrade that takes less than two minutes. The SpectraMax Paradigm reader can do absorbance, fluorescence, time-resolved fluorescence (including HTRF), fluorescence polarization, AlphaScreen®, AlphaLISA®, and luminescence measurements. Detection cartridge modularity allows you to configure the system to meet your current needs, while providing flexibility to address future applications.

Request a Quote for This Setup