APPLICATION NOTE
Functional characterization of 3D neurospheres assembled using iPSC-derived neurons and astrocytes
Neural organoids and 3D spheroids are a rapidly developing technology with great potential for understanding brain development and neuronal diseases.
They provide a more advanced and biologically relevant system for basic research and high-throughput drug discovery, including compound profiling and toxicity testing. In this application note, we describe methods for assembling normal human iPSC-derived cell types, including glutamatergic neurons, GABAergic neurons, and astrocytes into 3D neurospheres for compound profiling.
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Imaging
Product primary application
FLIPR Calcium Assay Kits; FLIPR Penta High-Throughput Cellular Screening System; ImageXpress Micro Confocal High-Content Imaging System
CMP
701Rn0000074KDtIAM
Title
Functional characterization of 3D neurospheres assembled using iPSC-derived neurons and astrocytes
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