APPLICATION NOTE
Functional analysis of spontaneous calcium oscillations of iPSC-derived 3D neural organoids
HPSC-derived neural organoids can help scientists understand brain development, disease, and disorders within the context of diverse genetic backgrounds.
The study explores the use of 3D neural organoids derived from human pluripotent stem cells (hPSCs) to evaluate neurotoxicity and neural function. Organoids were analyzed using imaging to track spontaneous calcium oscillations to provide insights into neural activity. The study highlights the benefits of high-throughput screening, automated monitoring, and the ability to test various compounds, to demonstrate the potential of this advanced model for drug testing and understanding brain function.
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Product family
FLIPR
Product primary application
CellXpress.ai; FLIPR Penta High-Throughput Cellular Screening System; FLIPR Calcium Assay Kits; ImageXpress Micro Confocal High-Content Imaging System
CMP
701Rn00000TzDZ8IAN
Title
Functional analysis of spontaneous calcium oscillations of iPSC-derived 3D neural organoids
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