APPLICATION NOTE
Assessing viability and real-time apoptosis/necrosis in an in vitro model of malignant glioma
Discover the fundamental steps involved in a miniature-scale compound screening tailored for cancer and pharmacological research
Malignant gliomas, a subset of aggressive brain tumors, represent a formidable challenge in the realm of oncology due to their invasive nature and resistance to conventional treatments. As researchers strive to unravel the intricacies of these tumors, assessing the viability and understanding the real-time dynamics of apoptosis and necrosis in malignant glioma cells emerges as a crucial focal point.
In this application note, we showcase the utility of the CellTiter-Glo® 2.0 Cell Viability Assay paired with the SpectraMax® i3x reader, offering a powerful solution for the preliminary screening of compounds.