![Screening of Cell Lines for Monoclonality](./media_117b0fe30bc41abbc2fb6caf2c53d8beb06736f8c.jpeg?width=750&format=jpeg&optimize=medium)
APPLICATION NOTE
Single-cell dispensing and screening of cell lines for monoclonality verification using the impedance-based single-cell dispenser and high-throughput fluorescence-based imager
![Single-cell dispensing and screening of cell lines](./media_1bf80e90a19650264525d1bd779c40f6d014efc7a.png?width=750&format=png&optimize=medium)
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There is an unmet need in the industry for a device that allows the fast and efficient isolation of single cells while preserving their integrity and providing insurance for their clonality. Performing gene editing, single-cell dispensing, and screening to develop a stable monoclonal cell line is a long and labor-intensive process. The optimization of these steps through different approaches, such as high-throughput screening and/or automation, can increase the efficiency and yield of the monoclonal cell-line development process. In this poster, we show the impedance-based single-cell dispenser and automated fluorescence-based high-throughput imaging screening to obtain monoclonal cell lines through robust single-cell selection.