MetaMorph Microscopy Automation & Image Analysis Software
MetaMorph® Microscopy Automation & Image Analysis Software is the industry standard for automated microscope acquisition, device control, and image analysis, bringing microscopists greater understanding of cell morphology, function, and behavior for over 25 years. It is the ideal "glue" for easily integrating dissimilar fluorescent microscope hardware and peripherals into a signle custom workstation, while providing all the tools needed to perform meaningful analysis of acquired images. The software offers many user-friendly application modules for biology-specific analysis such as cell signaling, cell counting, and protein expression.
MetaMorph Super-Resolution System - discern object details smaller than 250 nm in real-time! Learn more.
MetaMorph® Microscopy Automation & Image Analysis Software features:
- Real-time super-resoution image processing supported by GPU hardware acceleration. Resolve sub-cellular objects as small as 20 nm spatially and 40 nm axially. More information >
Image courtesy of Adel Kechkar, Deepak Nair, Daniel Choquet, Jean-Baptiste Sibarita, University of Bordeaux, Interdisciplinary Institute for Neuroscience, CNRS UMR 5297, F-33000. Bordeaux, France.
- Largest set of supported hardware device drivers allows researchers to build custom imaging systems to meet their specific application need.
- Multi-dimensional acquisition (MDA) module allows users to easily perform complex acquisition sequences using a simple, guided user interface.
- Integrated morphometric analysis (IMA) measures and categorizes objects into discreet user-definable classes, based on any combination of morphometric parameters, such as shape, size, or optical density.
- Linked images, graphs, and tables allow users to easily view, classify, and correlate images with extracted data.
- Device and camera streaming is a proprietary technology to accelerate image capture, maximizing hardware rate and peripheral device synchronization during acquisition. This leverages a camera's ability to simultaneously transfer images to memory during image acquisition, capturing dynamic cellular events in applications such as calcium ratio imaging.
- Custom journals enables you to further automate acquisition, processing, and analysis routines. Each journal will record and save a series of tasks without the need for programming. A graphical editor allows you to easily create and edit journals using a drag-and-drop interface.
- 4D viewer with 3D measurements facilitates visualization of multi-dimensional data sets, stacks, and sequential images. Users can simultaneously view multiple Z sections, wavelengths, time points, and positions in a single intuitive viewing window, as well as binarize multidimensional image data into discrete objects for 3D isosurface viewing and rotation. Isosurfaced objects selected by mouse are linked to an interactive spreadsheet of 3D object measurements, including volume, intensity, and several other measurement parameters.
- Scan slide module is ideal for large tissue samples, automatically acquiring multiple images larger than the field of view and then stitching them together. The unique ability of the MetaMorph Software to scan a defined area based on two distinct points (upper left and lower right corners) ensures you reproducibly capture high resolution images while taking the guess work out of tiling experiments.
- Live replay captures real time events such as in FRAP, FRET and other laser-based studies, time lapse experiments, live cell imaging, and digital microscopy. Buffering a specified duration of recent live video to memory allows the interactive capture of complete events of interest, including the buffered duration leading up to the event.
- Standard image enhancements emphasize image characteristics that may not be discernable in the original image, making subsequent analysis and presentation more informative. Standard tools include standard kernel and morphometric filters, image arithmetic, and stack visualization.